เทคโนโลยีและนวัตกรรมที่พร้อมถ่ายทอด
Process for Freeze-Drying the Clear Solution of Probiotic Strains for Cosmetic Products
Origin and Importance
The research team from Walailak University, led by Assoc. Prof. Dr. Chonticha Romyasamit, has developed an innovative facial essence product using Lacticaseibacillus paracasei T0901, a probiotic strain isolated from fermented palm sap in Thailand. This strain exhibits unique bioactive properties, including melanin reduction, anti-inflammatory effects, and acne prevention, making it a prime ingredient for natural skincare solutions. This innovation aligns with the increasing demand for eco-friendly skincare products that address environmental factors such as pollution and UV exposure, which are key contributors to skin damage.
Technology
The facial essence product is formulated using cell-free supernatants (CFS) from Lacticaseibacillus paracasei T0901, a probiotic strain isolated from fermented palm sap. The CFS demonstrates exceptional bioactive properties, including the ability to inhibit melanin production, reduce inflammation, and combat Cutibacterium acnes. It also balances the skin’s pH, enhances hydration, and strengthens the skin’s natural barrier.
To ensure stability and efficacy, the CFS undergoes a freeze-drying process. This innovative method involves cultivating the probiotic, extracting and filtering the CFS, and freeze-drying it to maintain its bioactive properties. The process preserves the CFS’s functionality, including its antioxidant and anti-inflammatory effects, while ensuring long-term stability and cost-efficiency. Rigorous testing throughout the development process guarantees that the final product meets consumer expectations for safe, high-quality, and natural skincare solutions.
รูปภาพ

Name of Researcher/School of Study
Name of Researcher : Assoc. Prof. Dr. Chonticha Romyasamit
School : School of Allied Health Sciences, Walailak University
Intellectual Property Type
Petty patent, Application Number 2403001870
Advantages / Highlights
- Natural skincare innovation powered by probiotics.
- Effective in addressing skin concerns like hyperpigmentation, acne, and inflammation.
- Cost-efficient with long-term stability through advanced freeze-drying technology.